Congress remains only 16 percent female, and Massachusetts has an especially long and rotten history of women in politics. Since Puritans settled there in the early 17th century, more Massachusetts women have been hanged in the Salem witch trials (14) than have been elected to the House of Representatives (4), the Senate (0) or the governor’s mansion (0, though Jane Swift served as acting governor from 2001 to 2003)
I think Warren has to be favored against Brown. Because he's a Republican who won in Massachusetts, Brown has the rep as a great politician, but I think he benefited from a perfect storm of (a) a historically good year for Republicans and (b) an incredibly uninspiring Democratic opponent in Martha Coakley (see also: Robert Ehrlich winning the Maryland governor's mansion in 2002 against Kathleen Kennedy Townsend). Obviously, he's component, but I don't think he's anything special. And while inexperienced candidates always have the potential to flame out in spectacular fashion, I think Warren has a ton of upside. And in this time of economic crisis, it'd be good to have one of America's foremost experts on bankruptcy in a position of influence.